First BAL | Second BAL | Third BAL | p‐value¶ | |
Total cell count ×103 | 184±38 | 195±43 | 189±55 | 0.66 |
Alveolar macrophage % | 83±9 | 71±11* | 77±16 | 0.033 |
Neutrophils % | 11±5 | 22±9* | 15±7 | 0.008 |
Total protein µg·mL−1 | 148±62 | 381±288* | 353±215* | 0.00077 |
Albumin µg·mL−1 | 40±19 | 131±95* | 118±67* | <0.0001 |
Albumin/total protein % | 28 | 34 | 33 | 0.12 |
PAF pg·mL−1 BAL | 1±3 | 93±115* | 33±39*,# | <0.0001 |
PAF-AcH nmol PAF·mL−1 BAL·min−1 | 0.05±0.02 | 0.56±0.15* | 0.13±0.06* | <0.0001 |
Total PL µg·mL−1 BAL | 2.7±1.1 | 1.4±0.6* | 1.2±0.7*,# | <0.0001 |
PC % of total PL | 71±5 | 56±6* | 60±8*,# | <0.0001 |
PG % of total PL | 10±3 | 6±1* | 6±2* | <0.0001 |
SM % of total PL | 6±1 | 17±3* | 16±4* | <0.0001 |
PE % of total PL | 4±1 | 6±2* | 5±1# | 0.0007 |
PS % of total PL | 4±2 | 6±1* | 6±1* | 0.002 |
PI % of total PL | 5±2 | 7±2* | 7±2* | 0.008 |
Lyso-phosphatidylcholine % of total PL | 0 | 2±1 | 0 | <0.0001 |
Values are presented as mean±sd
PAF: platelet activating factor
AcH: acetylhydrolase
PL: phospholipids
PC: phosphatidylcholine
PG: phosphatidylglycerol
SM: sphingomyelin
PE: phosphatidylethanolamine
PS: phosphatidylserine
PI: phosphatidylinositol
First BAL, second BAL and third BAL signify the time of receiving the data
*: significantly different from first BAL (p<0.05)
#: significantly different from second BAL (p<0.05)
¶: p‐values refer to the result of the repeated measures one-way analysis of variance comparisons among the three consecutive BAL results