Controls | IPF | Sarcoidosis | |||
Group 1 | Group 2 | Group 3 | |||
Patients n | 15 | 15 | 16 | 14 | 14 |
Age yrs | 45.6±1.9 | 66.5±3.1 | 37.6±2.7 | 40.4±3.4 | 54.6±4.5 |
Sex M:F | 13:2 | 11:4 | 9:7 | 6:8 | 7:7 |
Lymphadenopathy | Yes | Yes | No | ||
Pulmonary infiltrates | No | Yes | Yes | ||
Radiographic stage | 1 | 2 | 3/4 | ||
FEV1 % pred | 102.7±2.5 | 79.6±4.6** | 103±3.4 | 95.2±4.6 | 81.7±3.4** |
FVC % pred | 101.8±2.2 | 76.6±5.3** | 104.8±3.6 | 96.9±4.1 | 87.2±3.2 |
DL,CO % pred | 96.3±2.2 | 52.9±5.1** | 90.9±3.2 | 88.1±3.4 | 61.3±4.8** |
Data are presented as mean±sem unless otherwise stated
IPF: idiopathic pulmonary fibrosis
M: male
F: female
FEV1: forced expiratory volume in one second
FVC: forced vital capacity
DL,CO: diffusion capacity of carbon monoxide
**: p<0.01 compared with controls