Table 2—

Synopsis of current trials of prone positioning

First author [ref.]TypeYearPatient nPrevalent diseaseSupportImproved patients %Pa,O2 supine kPaPa,O2 prone kPaSurvival %
Piehl 4R19765MFA1009.6±1.714.1±1.260
Douglas 5P19776MFA1008.4±1.318.4±8.950
Gattinoni 18P199110MFA309.3±0.915.4±4.360
Pelosi 22P199817PRFA7613.3±3.516.6±3.659
Blanch 23P199723MNS679.3±3.6#12.0±7.052
Servillo 24P199712SFA8316.4±2.920.3±2.342
Guerin 25P199912UFA6718.1±2.327.1±3.258
Langer 26P198813MU629.2±1.114.8±2.754
Chatte 27P199732PRU3113.3±4.823.9±4.944
Gattinoni 28P199754MFA7616.4±5.3#25.9±9.354
Germann 39P199847PRU7415.321.991
Papazian 40P199814PRU6417.0±5.9#25.7±11.085
Martinez 41P199914PRFA4114.6±7.3#21.4±11.843
Dupont 42P200027MU7412.2±3.5#22.5±10.137
Jolliet 43P199712PRU588.2±0.99.6±1.933
Albert 50R19939MFA788.4±2.030.7±16.1
Walz 51R199216UU100
Shichinohe 52R19917UU100
Thulig 53C19911UU1008.911.8
Faller 54L19883UU10013.7±3.326.2±3.9
Manara 55L19874UU7539.9±7.0+19.0±2.025
Pappert 56P199412SNS569.8±1.516.4±3.958
Vollman 57P199615PRU6011.6±1.913.6±4.4
Brussel 58P199310UU749.7±3.913.4±5.290
Voggenreiter 59P199922UU9019.8±1.1#39.5±4.082
Wenz 60P200010MU8020.0±4.929.3±2.390
Friedrich 61P199620MU6012.9±0.520.2±2.090
Mure 62P199713SFA9269.7±18.1+34.3±18.869
Flaatten63P199814SFA9011.7±0.818±1.457
  • P: prospective

  • R: retrospective

  • C: case report

  • L: letter

  • M: primary/secondary acute respiratory distress syndrome (ARDS) between 20–80%

  • PR: >80% primary ARDS

  • S: >80% secondary ARDS

  • U: data not available

  • FA: free abdomen

  • NS: not supported

  • Pa,O2: arterial oxygen pressure

  • #: arterial oxygen tension/inspiratory oxygen fraction

  • : median

  • +: alveolar-arterial oxygen pressure difference