Table 1—

Invasive and noninvasive tests of respiratory muscle strength

ControlsUDW/BDWIMWCMW
Age yrs35.3±10.254.0±16.8*66.2±11.9*39.2±14.3
Subjects n (female)6 (1)10 (0)12 (1)5 (3)
Poes,sniff cmH2O129.9±26.885.5±24.7*34.4±8.9*39.2±11.3*
Pgas,cough cmH2O175.6±58.9229.6±61.0175.8±70.348.3±18.3*
PI,max % pred (cmH2O)91.8±17.6 (112.0±27.6)71.5±18.9* (82.2±15.9)28.1±11.9* (29.5±10.3)41.7±22.0* (33.8±15.8)
PE,max % pred (cmH2O)99.3±31.5 (143.1±49.6)77.8±14.9 (110.4±30.0)63.6±32.5* (90.9±48.0)32.0±21.4* (32.4±16.3)
  • Data are presented as mean±sd unless otherwise stated

  • UDW/BDW: isolated unilateral and bilateral diaphragm weakness

  • IMW: generalised inspiratory muscle weakness

  • CMW: combined inspiratory and expiratory muscle weakness

  • Poes,sniff: maximum sniff oesophageal pressure

  • Pgas,cough: maximum cough gastric pressure

  • PI,max: maximum inspiratory pressure averaged over 1 s

  • % pred: percentage of predicted normal value

  • PE,max: maximum expiratory pressure averaged over 1 s

  • *: significant difference from control group, p<0.05