Effects of dextran on haemodynamic and blood gas data
| Q | Hyperoxia | Hypoxia | |||
| Baseline | Dextran | Baseline | Dextran | ||
| SAP mmHg | HQ | 116±6 | 106±3 | 91±8¶ | 102±7 |
| LQ | 65±6 | 78±8 | 56±8¶ | 57±5 | |
| LAP mmHg | HQ | 7±1 | 10±1# | 7±1 | 9±1# |
| LQ | 5±1 | 6±1# | 4±1 | 6±1# | |
| fC beat·min−1 | HQ | 126±9 | 126±9 | 140±11¶ | 137±11¶ |
| LQ | 130±11 | 144±15 | 163±11¶ | 171±11¶ | |
| Q L·min−1·m−2 | HQ | 4.4±0.4 | 5.4±0.5 | 4.1±0.4 | 5.4±0.5¶ |
| LQ | 2.1±0.2 | 2.6±0.3 | 2.2±0.3 | 2.6±0.2 | |
| PAP mmHg | HQ | 18±1 | 22±1# | 37±2¶ | 39±2¶ |
| LQ | 11±1 | 13±1# | 19±1¶ | 19±1¶ | |
| Pa,O2 kPa | HQ | 29±1.3 | 31.7±4.5 | 5±0.4¶ | 5.2±0.4¶ |
| LQ | 29.6±2.7 | 32.4±4.9 | 5.3±0.4¶ | 5.9±0.4¶ | |
| Pa,CO2 kPa | HQ | 5.2±0.3 | 4.9±0.1 | 4.7±0.1 | 4.9±0.1 |
| LQ | 4.7±0.1 | 4.4±0.3 | 4.7±0.1 | 4.4±0.1 | |
| pH | HQ | 7.43±0.01 | 7.40±0.01# | 7.44±0.10¶ | 7.39±0.01#,¶ |
| LQ | 7.45±0.01 | 7.41±0.01# | 7.40±0.01¶ | 7.36±0.02#,¶ | |
| Venous PO2 kPa | HQ | 6.1±0.3 | 6.3±0.3 | 3.3±0.4¶ | 2.5±0.4¶ |
| LQ | 4.5±0.5 | 4.1±0.4 | 2.3±0.1¶ | 2.3±0.1¶ | |
| Haemoglobin g·dL−1 | HQ | 8.0±0.2 | 5.3±0.4# | 9.0±0.4 | 6.2±0.5# |
| LQ | 9.0±0.4 | 5.7±0.4# | 9.4±0.5 | 7.0±0.7# | |
| Osmolality mOsm·L−1 | 269±16 | 287±11 | 255±23 | 263±32 | |
| PVR mmHg·min−1·m2·L−1 | HQ | 2.5±0.1 | 2.2±0.2 | 7.3±0.5¶ | 5.6±0.4¶ |
| LQ | 2.9±0.2 | 2.7±0.3 | 6.8±0.5¶ | 5.5±0.4¶ | |
Data are presented as mean±sd, n=9
Q: cardiac output
HQ and LQ: highest and lowest cardiac output respectively
SAP: systemic arterial pressure
LAP: left arterial pressure
fC: cardiac frequency
PAP: pulmonary arterial pressure
Pa,O2: oxygen tension in arterial blood
Pa,CO2: carbon dioxide tension in arterial blood
PO2: partial pressure of oxygen
PVR: pulmonary vascular resistance
Significant difference #: p<0.05 between baseline and dextran at the same level of Q
¶: p<0.05 between hyperoxia and hypoxia at the same step