Effects of sodium chloride (NaCl) with dextran on haemodynamic and blood gas data
| Q | Hyperoxia | Hypoxia | |||
| Baseline | NaCl/dextran | Baseline | NaCl/dextran | ||
| SAP mmHg | HQ | 126±7 | 113±8 | 112±8 | 102±8 |
| LQ | 72±7 | 77±10 | 50±3 | 61±7 | |
| LAP mmHg | HQ | 7±1 | 8±1 | 9±1 | 9±1 |
| LQ | 6±1 | 7±1 | 6±1 | 6±1 | |
| fC beat·min−1 | HQ | 142±12 | 136±15 | 141±12 | 154±11# |
| LQ | 160±15 | 179±14 | 158±17 | 183±11# | |
| Q L·min−1·m−2 | HQ | 4.1±0.3 | 3.8±0.3 | 3.9±0.3 | 3.8±0.3 |
| LQ | 2.1±0.4 | 1.9±0.3 | 2.0±0.2 | 1.8±0.2 | |
| PAP mmHg | HQ | 20±1 | 20±2 | 33±3¶ | 38±2¶,# |
| LQ | 15±1 | 14±2 | 23±4 | 25±4 | |
| Pa,O2 kPa | HQ | 37±4 | 37±4.5 | 4.8±0.3¶ | 5.7±0.4¶,# |
| LQ | 27.6±4.7 | 24.1±2.7 | 5.6±0.4¶ | 5.6±0.4¶ | |
| Pa,CO2 kPa | HQ | 5.2±0.1 | 5.5±0.3 | 5.0±0.1 | 5.2±0.3 |
| LQ | 5.3±0.3 | 4.4±0.1 | 4.9±0.3 | 4.7±0.3 | |
| pH | HQ | 7.46±0.02 | 7.38±0.02# | 7.44±0.02¶ | 7.40±0.02 |
| LQ | 7.43±0.02 | 7.38±0.02# | 7.37±0.03¶ | 7.38±0.02 | |
| Venous PO2 kPa | HQ | 6.5±0.5 | 6.0±0.4 | 3.7±0.4¶ | 2.9±0.3¶ |
| LQ | 3.9±0.6 | 3.1±0.4 | 1.7±0.2 ¶ | 1.8±0.1¶ | |
| Haemoglobin g·dL−1 | HQ | 9.2±0.4 | 8.1±0.6# | 9.0±0.4 | 7.8±0.6# |
| LQ | 9.0±0.7 | 7.9±0.7# | 9.2±0.6 | 8.0±0.7# | |
| Osmolality mOsm·L−1 | 298±3 | 286±14 | 292±18 | 286±19 | |
| PVR mmHg·min·m2·L−1 | HQ | 3.2±0.2 | 3.2±0.2 | 6.2±0.4¶ | 7.6±0.4¶ |
| LQ | 4.3±0.3 | 3.8±0.3 | 8.5±0.5¶ | 10.3±0.4¶ | |
Data are presented as mean±sd, n=9
Q: cardiac output
HQ and LQ: highest and lowest cardiac output respectively
SAP: systemic arterial pressure
LAP: left arterial pressure
fC: cardiac frequency
PAP: pulmonary arterial pressure
Pa,O2: oxygen tension in arterial blood
Pa,CO2: carbon dioxide tension in arterial blood
PO2: partial pressure of oxygen
PVR: pulmonary vascular resistance
Significant difference #: p<0.05 between baseline and NaCl with dextran at the same level of Q
¶: p<0.05 between hyperoxia and hypoxia at the same step