Table 6—

Ventilatory function and airway responsiveness in 1992–1993 and 1998–1999, by atopic status

NonatopicAtopic
1992–19931998–1999p-value1992–19931998–1999p-value
Mean FEV1 % pred (SEM)103.4 (0.69)104.9 (0.72)0.13101.6 (1.2)103.1 (0.99)0.32
PD20 <6400 µg30.626.50.18757.543.20.01
PD20 <1000 µg16.410.60.01441.130.70.052
PD20 <200 µg5.83.50.11519.217.10.62
Geometric mean DRS0.003770.002720.0040.01450.008320.038
  • Data are presented as % unless otherwise stated.

  • FEV1: forced expiratory volume in one second

  • PD20: provocative concentration causing a 20% fall in FEV1

  • DRS: dose/response slope