Table 2—

Lung function, airway responsiveness levels, and atopy

1992–19931998–1999p-value
Mean FEV1 % pred (SEM)102.9 (0.59)104.3 (0.58)0.09
PD20 <6400 µg37.231.60.041
PD20 <1000 µg22.516.60.01
PD20 <200 µg9.17.60.338
Geometric mean DRS0.005270.003790.004
Atopic#24.831.10.015
  • Data are present as % unless otherwise stated.

  • FEV1: forced expiratory volume in one second

  • PD20: provocative concentration causing a 20% fall in FEV1

  • DRS: dose/response slope.

  • #: at least one positive allergen skin test (wheal≥4 mm greater than that of saline control) 10