Table 3—

Change in sputum Pseudomonas aeruginosa density following 4 weeks of nebulised antibiotic therapy

Log10 cfu·mL−1Change from baseline
ITT population
 Patients assessed at week 4 n5050
 p-value (within)#<0.0010.007
Microbiologically-evaluable patients
 Assessed at week 4 n4237
 p-value (within)#<0.0010.049
  • TNS: tobramycin nebuliser solution

  • cfu: colony forming unit

  • ITT: intent-to-treat

  • #: between-group testing using the Wilcoxon rank-sum test