Table 1—

Baseline characteristics of patients

CharacteristicTNSColistinp-value
Patients n5362
Sex
 Male20 (37.7)32 (51.6)0.136#
 Female33 (62.3)30 (48.4)
Age yrs
 Mean±sd21.3±9.620.1±9.40.505
 Median (range)20.0 (7–42)18.0 (8–50)
DNase use36 (67.9)34 (45.2)ND
Nebulised antibiotic in previous 6 months#48 (90.6)50 (80.6)ND
FEV1 % pred55.4±22.959.4±22.60.349
FVC % pred72.5±21.776.40±19.20.327
Log10 cfu·mL−1+6.30±1.526.77±1.340.077
  • Data are presented as mean±sd and n (%) unless otherwise stated

  • DNase: deoxyribonuclease

  • TNS: tobramycin nebuliser solution

  • FEV1: forced expiratory volume in one second

  • FVC: forced vital capacity

  • ND: not done

  • cfu: colony forming unit

  • #: Chi-squared test

  • : paired t-test

  • +: sputum Pseudomonas aeruginosa density