Table 2—

Respiratory responses to chemical stimuli in control subjects and patients with obstructive sleep apnoea-hypopnoea syndrome (OSAHS)

Control subjectsPatients with OSAHS
ΔVI/Sa,O2/BSA L/min/%/m20.455±0.0060.261±0.003**
ΔP0.1/Sa,O2 kPa/%0.0033±0.00030.0024±0.0004**
ΔVI,N/BSA L/min/m25.45±0.365.43±0.46
ΔVI,0/BSA L/min/m210.9±1.786.55±0.78**
ΔVI/BSA L/min/m23.60±0.501.57±0.30**
ΔVI %33.0±2.824.0±3.6**
  • Data are presented as mean±sd

  • ΔVI/Sa,O2/BSA: ventilatory response to progressive isocapnic hypoxic stimulation

  • ΔP0.1/Sa,O2: central inspiratory drive response to progressive isocapnic hypoxic stimulation

  • ΔVI,N/BSA: inspiratory minute ventilation during room air breathing

  • ΔVI,0/BSA: inspiratory minute ventilation during mildly hypercapnic hypoxic state

  • ΔVI: withdrawal response

  • **: p<0.01 for the comparison with control group