Variable | Original model | Added variable | ||||
CHD history | COPD history | Sex | Smoking | AHI | ||
Age | ||||||
<50 yrs | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
50–60 yrs | 1.50 (0.71–3.16) | 1.52 (0.72–3.20) | 1.50 (0.71–3.18) | 1.52 (0.72–3.21) | 1.58 (0.74–3.34) | 1.54 (0.73–3.24) |
>60 yrs | 3.02 (1.41–6.48)* | 2.99 (1.39–6.43)* | 2.48 (1.13–5.46)* | 3.29 (1.51–7.16)* | 3.50 (1.61–7.59)* | 3.20 (1.48–6.92)* |
BMI | ||||||
<28 kg·m−2 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
28–35 kg·m−2 | 1.12 (0.46–2.70) | 1.13 (0.47–2.72) | 1.14 (0.47–2.77) | 1.11 (0.46–2.67) | 1.08 (0.45–2.60) | 1.09 (0.45–2.63) |
>35 kg·m−2 | 1.84 (0.71–4.78) | 1.89 (0.72–4.95) | 1.88 (0.71–4.95) | 2.02 (0.77–5.34) | 2.02 (0.78–5.24) | 1.77 (0.67–4.63) |
AHT history | ||||||
No | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Yes | 1.06 (0.58–1.94) | 1.04 (0.56–1.91) | 1.18 (0.63–2.22) | 1.09 (0.59–2.00) | 1.16 (0.63–2.12) | 1.05 (0.57–1.93) |
SAHS treatment | ||||||
No | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Surgery | 0.15 (0.04–0.53)* | 0.16 (0.04–0.54)* | 0.19 (0.05–0.65)* | 0.16 (0.04–0.57)* | 0.17 (0.05–0.59)* | 0.14 (0.04–0.50)* |
Diet | 0.26 (0.12–0.54)* | 0.26 (0.12–0.55)* | 0.28 (0.13–0.59)* | 0.26 (0.12–0.54)* | 0.28 (0.13–0.58)* | 0.25 (0.12–0.52)* |
CPAP | 0.23 (0.09–0.58)* | 0.23 (0.09–0.58)* | 0.25 (0.10–0.62)* | 0.23 (0.09–0.59)* | 0.24 (0.09–0.60)* | 0.22 (0.08–0.55)* |
Added variable | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |
1.31 (0.50–3.40) | 1.50 (0.71–3.13)¶ | 1.51 (0.63–3.60) | 2.02 (0.98–4.18)# | 0.71 (0.33–1.50) | ||
2.62 (1.20–5.69)*,+ |
Data are presented as hazard ratio (95% confidence interval)
CHD: coronary heart disease
COPD: chronic obstructive pulmonary disease
AHI: apnoea/hypopnoea index
BMI: body mass index
AHT: arterial hypertension
SAHS: sleep apnoea/hypopnoea syndrome
CPAP: continuous positive airway pressure
*: p<0.05
#: p<0.10 and ≥0.05. Reference categories of variables added to the original model: no CHD history, no COPD history, female sex, no smoking habit and AHI ≥30
¶: COPD history forced expiratory volume in one second (FEV1) ≥50%
+:COPD history FEV1 <50%