Relationships between change on serial computed tomography (CT) and pulmonary function trends
| FEV1 r | FVC r | PO2 r | |
| Change in: | |||
| Bronchiectasis | −0.37 (p=0.01) | −0.32 (p=0.03) | −0.27 (p=0.18) |
| Bronchial wall thickness | −0.25 (p=0.09) | −0.35 (p=0.02) | ns |
| Plugging of large airways | −0.40 (p<0.005) | −0.34 (p=0.02) | −0.39 (p<0.05) |
| Plugging of small airways | −0.23 (p=0.12) | −0.40 (p<0.005) | ns |
| Combined plugging score | −0.46 (p<0.001) | −0.52 (p<0.0005) | −0.42 (p=0.03) |
| Decreased attenuation | ns | ns | ns |
FEV1: forced expiratory volume in one second
FVC: forced vital capacity
PO2: oxygen tension
ns: nonsignificant
Changes in carbon monoxide diffusing capacity of the lung and carbon monoxide transfer coefficient were not linked to serial change in any CT feature