Table 1—

Patient characteristics at screening

Patient no.	Age yrs	Sex	Baseline FEV₁ L	Baseline FEV₁ % pred	Log₂ PC₂₀ methacholine	Log₂ PC₂₀ NKA
	22	F	2.57	72.0	−6.71	−12.92
2	20	F	3.56	93.9	−6.51	−15.65
3	32	M	3.67	90.0	−5.25	−16.04
4^#	28	F	3.12	97.8	−5.92	−12.39
5	49	M	3.28	92.9	−5.35	−14.28
6^#	25	F	3.26	103.8	−5.61	−11.83
7	37	M	2.85	71.3	−5.92	−13.29
8	23	F	2.30	70.6	−7.06	−10.30
9	27	F	3.10	90.6	−6.14	−10.73
10^#	18	F	3.24	94.2	−5.10	−10.17
11	21	M	4.19	90.9	−5.96	−12.26

FEV₁: forced expiratory volume in one second
PC₂₀: provocative concentration causing a 20% fall in the FEV₁
NKA: neurokinin A
F: female
M: male
^#: patient stopped inhaled-steroid treatment at least 4 weeks prior to visit one