Table 1—

Characteristics of subjects

Patient no.SexAge yrsFEV1# % predPC20FEV1 mg·mL−1Cold score+Antibody titre§ pre/postCultureƒ days −2/3/6
1F2199.3>163<1/32neg/neg/neg
2M20110.3>1691/128neg/RV16/RV16
3F20108.5>1622/128neg/RV16/RV16
4M24104.5>166<1/1neg/RV16/RV16
5F21105.8>1641/8neg/RV16/RV16
6M2297.9>1651/4neg/RV16/RV16
7M20100.1131<1/8neg/neg/neg
8M23107.5>161<1/8neg/RV16/RV16
9M19107.1>1631/8neg/neg/neg
10M2187.1>1622/2neg/neg/neg
11M2099.9>1621/4neg/RV16/RV16
12M2797.9>165<1/8neg/RV16/RV16
  • FEV1: forced expiratory volume in one second

  • PC20 FEV1: provocation concentration causing a 20% fall in FEV1

  • M: male

  • F: female

  • #: FEV1 % from predicted

  • : airway responsiveness to methacholine measured at baseline

  • +: total cold score at the time point with the highest score (between days 0–5)

  • §: titre (circulating antibodies against RV16) before and 4 weeks after inoculation (e.g. pre/post=1:1/1:4=1/4)

  • ƒ: rhinovirus culture of nasal washing fluid