Patient no. | Sex | Age yrs | FEV1# % pred | PC20FEV1¶ mg·mL−1 | Cold score+ | Antibody titre§ pre/post | Cultureƒ days −2/3/6 |
1 | F | 21 | 99.3 | >16 | 3 | <1/32 | neg/neg/neg |
2 | M | 20 | 110.3 | >16 | 9 | 1/128 | neg/RV16/RV16 |
3 | F | 20 | 108.5 | >16 | 2 | 2/128 | neg/RV16/RV16 |
4 | M | 24 | 104.5 | >16 | 6 | <1/1 | neg/RV16/RV16 |
5 | F | 21 | 105.8 | >16 | 4 | 1/8 | neg/RV16/RV16 |
6 | M | 22 | 97.9 | >16 | 5 | 1/4 | neg/RV16/RV16 |
7 | M | 20 | 100.1 | 13 | 1 | <1/8 | neg/neg/neg |
8 | M | 23 | 107.5 | >16 | 1 | <1/8 | neg/RV16/RV16 |
9 | M | 19 | 107.1 | >16 | 3 | 1/8 | neg/neg/neg |
10 | M | 21 | 87.1 | >16 | 2 | 2/2 | neg/neg/neg |
11 | M | 20 | 99.9 | >16 | 2 | 1/4 | neg/RV16/RV16 |
12 | M | 27 | 97.9 | >16 | 5 | <1/8 | neg/RV16/RV16 |
FEV1: forced expiratory volume in one second
PC20 FEV1: provocation concentration causing a 20% fall in FEV1
M: male
F: female
#: FEV1 % from predicted
¶: airway responsiveness to methacholine measured at baseline
+: total cold score at the time point with the highest score (between days 0–5)
§: titre (circulating antibodies against RV16) before and 4 weeks after inoculation (e.g. pre/post=1:1/1:4=1/4)
ƒ: rhinovirus culture of nasal washing fluid