Table 1—

Differential cell counts in bronchoalveolar lavage fluid (BALF) in controls and in subjects with fibrosing alveolitis (FA) before and after N-acetylcysteine (NAC) treatment

Healthy controlsFA before NACFA after NAC
Subjects n81818
Total cell count 104·mL BALF−17.1±1.0*18.4±1.521.2±1.6
AM 104·mL BAL F−16.6±0.7*12.9±1.214.1±1.3
AM %93.3±2.7*71.5±4.671.1±4.3
PMN 104·mL BALF−10.3±0.09*2.3±0.52.8±0.5
PMN %4.3±1.4*12.3±2.312.1±1.6
EOS 104·mL BALF−10.05±0.03*0.8±0.30.8±0.2
EOS %0.9±0.7*3.8±1.24.2±1.3
Mast 104·mL BALF−100.06±0.030.11±0.04
Mast %00.3±0.20.5±0.2
lym 104·mL BALF−10.12±0.09*2.3±0.93.4±1.5
lym %1.6±1.2*12.1±3.912.2±3.9
  • Data are presented as mean±sem unless otherwise stated

  • AM: alveolar macrophages

  • PMN: neurophilic granulocytes

  • EOS: eosinophilic granulocytes

  • Mast: mast cells

  • lym: lymphocytes

  • *: p<0.05 versus FA before and after NAC