Table 1

Clinical status of the patients

<3 months post LTBOSnon-BOS
Patients n748
Age on the day of bronchoscopy41±343±842±5
Time since transplant months1.4±0.323.3±8.615.9±2.3
Sex F:M6:11:33:5
Underlying disease n
 Emphysema223
 Pulmonary fibrosis512
 Cystic fibrosis11
 Primary pulmonary hypertension1
 Lymphangioleiomyomatosis1
Type of transplant n
 Single lung634
 Double lung113
 Heart and lung1
FEV1 before bronchoscopy % of baseline99.3±0.676.0±6.598.9±2.1
FEF25%–75% before bronchoscopy % of baseline99.4±0.560.5±9.897.4±0.8
Immunosuppression at the time of bronchoscopy n of patients treated with
 Cyclosporin A/Azathioprin/Prednisolon510
 Cyclosporin A/Mycophenolatmofetil/Prednisolon200
 Tacrolimus/Azathioprin/Prednisolon038
  • Data are presented as mean±sem unless otherwise stated

  • LT: lung transplantation

  • BOS: bronchiolitis obliterans syndrome

  • F: female

  • M: male

  • FEV1: forced expiratory volume in one second

  • FEF25%–75%: forced midexpiratory flow