p-Values (two-sided) for analyses comparing duration of exposure between mutation-positive and mutation-negative patients
| Excluding both sisters | Combining the sisters into one observation | Including both sisters as independent observations | |
| Comparing durations# | >0.05 | 0.032 | 0.012 |
| Comparing proportions of patients with duration <3 months versus ≥3 months¶ | >0.05 | 0.021 | 0.012 |
#: Mann-Whitney U-test
¶: Fisher's exact test