Table 2

Physiological effects of noninvasive positive pressure ventilation

Effect on respiratory mechanics
 Decreased negative deflections of intrathoracic pressure
 Decreased work of breathing
 Additive effects of positive pressure ventilation and external PEEP
Effects on gas exchange
 Improvement of hypoxaemia and hypercapnia secondary to slower and deeper breathing pattern
 No effects on ventilation/perfusion mismatch
  • PEEP: positive end-expiratory pressure