Genotype | Subjects n | Plasma levels of α1-AT | |||
Dresden | Munich | ||||
Median (min–max) mg·dL−1 | Median (mini–max) mg·dL−1 | ||||
PiMS genotype | 121 # | 132 (95–183) + | 134 (97–229) + | ||
PiMZ genotype | 80 # | 102 (71–187) +,§ | 101 (52–151) +,§ | ||
Others | 3040 # | 154 (83–254) | 153 (77–255) | ||
Total sample | 329¶ | 152 (71–254) | 152 (52–255) |
Pi: protein inhabitor
#: German children with measurements of α1-AT in plasma and α1-AT genotyping
¶: total number of German children with measurements of α1-AT in plasma
+: Wilcoxon p<0.001 as compared to others
§: Wilcoxon p<0.01 as compared to Pi MS genotype