Table 3—

Plasma levels of α1-antitrypsin (α1-AT) in children in Dresden and Munich according to the genotype

GenotypeSubjects nPlasma levels of α1-AT
DresdenMunich
Median (min–max) mg·dL−1Median (mini–max) mg·dL−1
PiMS genotype121 #132 (95–183) +134 (97–229) +
PiMZ genotype80 #102 (71–187) +,§101 (52–151) +,§
Others3040 #154 (83–254)153 (77–255)
Total sample329152 (71–254)152 (52–255)
  • Pi: protein inhabitor

  • #: German children with measurements of α1-AT in plasma and α1-AT genotyping

  • : total number of German children with measurements of α1-AT in plasma

  • +: Wilcoxon p<0.001 as compared to others

  • §: Wilcoxon p<0.01 as compared to Pi MS genotype