Pa,O2 kPa | Pa,CO2 kPa | FVC % pred | FEV1 % pred | FEV1/FVC % | |||
Room air | LTOT/HMV | Room air | LTOT/HMV | ||||
All patients | 8.08±1.79 | 11.34±2.59 | 6.11±1.10 | 5.85±1.31 | 54.1±22.1 | 39.6±18.8 | 0.58±0.19 |
COPD | 7.26±1.16+,§,ƒ | 10.42±2.09+,§,ƒ | 6.07±1.18 | 6.29±1.33¶,+,§,ƒ | 65.0±16.8¶,+,§,ƒ | 38.6±16.2¶,§ | 0.46±0.15+,§,ƒ |
Bronchiectasis | 7.34±1.18 +,§,ƒ | 10.68±1.87+,§,ƒ | 6.57±1.02 | 6.83±1.03#,+,§,ƒ | 54.0±20.0#,+,§ | 31.7±11.7#,+,ƒ | 0.49±0.11+,§,ƒ |
Neuromuscular disease | 10.09±2.06#,¶,§,ƒ | 12.52±2.25#,¶,ƒ | 6.13±1.15 | 4.86±1.24#,¶,§,ƒ | 30.4±22.2#,¶,§,ƒ | 35.4±22.5¶,§ | 0.76±0.13#,¶,§,ƒ |
Restrictive disorders | 8.58 ±1.71#,¶,+ | 12.20±2.79#,¶ | 6.03±0.92 | 5.60±0.99#,¶,+ | 50.9±20.2#,¶,+,ƒ | 45.5±21.8#,+ | 0.70±0.13#,¶,+,ƒ |
Mixed respiratory failure | 8.32±1.89#,¶,+ | 11.64±2.97#,¶ | 6.17±1.10 | 5.84±1.32#,¶,+ | 48.5±19.7#,+,§ | 37.8±17.5¶ | 0.64±0.17#,¶,+,§ |
ANOVA, p-value | <0.0001 | <0.0001 | ns | <0.0001 | < 0.0001 | <0.01 | < 0.0001 |
Data are presented as mean±sd
FVC: forced vital capacity
FEV1: forced expiratory volume in one second
Pa,O2: oxygen tension in arterial blood
Pa,CO2: carbon dioxide tension in arterial blood
ns: not significant
Analysis of variance (ANOVA) and posthoc test of Fisher
#: significantly different with chronic obstructive pulmonary disease (COPD) patients
¶: with bronchiectasis patients
+: with neuromuscular disease patients
§: with interstitial disease patients; and
ƒ: with mixed respiratory failure