Survival data of lung cancer patients according to different factors in the years 1968–1971 12 and 1990–1992
| Factor | 1968–1971 survey | 1990–1992 survey | Comparison between surveys | ||||
| n (%)+ | 2 yrs# | 5 yrs¶ | n (%)+ | 2 yrs# | 5 yrs¶ | ||
| All patients | 446 (100) | 66 (15) | 19 (4) | 602 (100) | 114 (19) | 72 (12) | n2 p=0.79, n5 p<0.001 |
| Male | 420 (94) | 62 (15) | 19 (4) | 510 (85) | 92 (18) | 59 (12) | |
| Female | 26 (6) | 4 (15) | 0 | 92 (15) | 22 (24) | 13 (14) | |
| Histological type | |||||||
| Squamous cell carcinoma | 198 (44) | 40 (20) | 12 (6) | 204 (34) | 54 (26) | 33 (16) | p<0.001 |
| Adenocarcinoma | 50 (11) | 9 (18) | 2 (4) | 135 (22) | 31 (23) | 25 (19) | p=0.006 |
| Small cell carcinoma | 115 (26) | 5 (4) | 2 (2) | 121 (20) | 9 (7) | 4 (3) | ns |
| Large cell carcinoma | 21 (5) | 2 (10) | 1 (5) | 23 (4) | 4 (17) | 2 (9) | ns |
| Other unclassified | 47 (11) | 7 (15) | 2 (4) | 33 (6) | 9 (27) | 6 (18) | ns |
| No histology | 15 (3) | 3 (20) | 0 (0) | 86 (14) | 7 (8) | 2 (2) | ns |
| Comparison between types | χ2logrank=67.9, p<0.001 | χ2logrank=59.2, p<0.001 | |||||
| TNM staging | 519 (86) | ||||||
| Stage I | 97 (19) | 56 (58) | 41 (42) | ||||
| Stage II | 21 (4) | 13 (62) | 7 (33) | ||||
| Stage IIIA | 57 (11) | 19 (33) | 10 (18) | ||||
| Stage IIIB | 128 (25) | 16 (13) | 10 (8) | ||||
| Stage IV | 216 (41) | 6 (3) | 2 (1) | ||||
| Comparison between stages | χ2logrank=199.6, p<0.001 | ||||||
| Treatment | |||||||
| Surgery | 71 (16) | 33 (46) | 17 (24) | 123 (20) | 79 (64) | 59 (48) | p<0.001 |
| Chemotherapy | 58 (13) | 3 (5) | 0 (0) | 20 (3) | 2 (10) | 1 (5) | ns |
| Radiotherapy | 150 (33) | 19 (13) | 2 (1) | 189 (32) | 22 (11) | 8 (4) | ns |
| Combination | 79 (18) | 9 (11) | 0 (0) | 54 (9) | 6 (11) | 2 (4) | ns |
| No treatment | 68 (20) | 2 (2) | 0 (0) | 216 (36) | 5 (2) | 0 (0) | ns |
| Comparison between treatment | χ2logrank=218.7, p<00.1 | χ2logrank=227, p<00.1 | |||||
| Symptomatic stages | 441 (99) | 517 (86) | |||||
| No symptoms | 70 (16) | 21 (30) | 7 (10) | 47 (9) | 25 (53) | 18 (38) | p<0.001 |
| Primary symptoms | 140 (32) | 30 (21) | 11 (8) | 141 (27) | 43 (30) | 30 (21) | p<0.001 |
| Systemic symptoms | 127 (29) | 13 (10) | 1 (1) | 217 (42) | 39 (18) | 18 (8) | p<0.001 |
| Metastatic symptoms | 104 (23) | 2 (2) | 0 (0) | 112 (22) | 1 (1) | 0 (0) | ns |
| Comparison between stages | χ2logrank=99, p<0.001 | χ2logrank=120, p<0.001 | |||||
+: Number of patients at the beginning (% of all patients in survey with data on factor considered)
#: number and percentage surviving for 2 yrs
¶: number and percentage surviving for 5 yrs
TNM: tumour, node, metastasis
ns: nonsignificant
χ2: chi-squared
n2: 2-yr survival rate comparison
n5: 5-yr survival rate comparison