Bax/B-cell lymphoma leukaemia-2 (Bcl-2) ratio
| Unstimulated PBT | IL-2 stimulated PBT | |||||
| Baseline | FP | p-value | IL-2 | FP+IL-2 | p-value | |
| Normals | ||||||
| 72 h | 1.7 (1.2–1.8) | 1.6 (1.3–2.3) | ns | 0.7 (0.6–0.8) | 1.2 (1.1–1.4) | ns |
| 144 h | 2 (1.4–2.5) | 2.1 (1.5–2.9) | ns | 0.8 (0.7–1) | 1.2 (1–1.5) | ns |
| Asthmatics | ||||||
| 72 h | 1.6 (0.9–2) | 1.8 (1.1–2.6) | ns | 0.5 (0.4–0.5) | 1 (0.9–1.2) | <0.04 |
| 144 h | 1.1 (1–1.8) | 1.9 (1.3–3.7) | <0.01 | 0.6 (0.4–0.6) | 1.2 (0.7–1.7) | <0.007 |
Data are presented as median (25–75 percentiles) unless where otherwise indicated
FP: fluticasone propionate
IL-2: interleukin-2
PBT: peripheral blood T-lymphocytes
ns: nonsignificant
Statistical analysis by ANOVA. Data were considered statistically significant when p<0.05