Table 5—

Comparison of clinical features of exacerbations with (LspH) and without (NLspH) serological evidence of infection with Legionella spp.

VariableLspHNLspHp‐value between groups
Subjects n40200
Increased dyspnoea (days before hospitalization)6.6±3.35.0±3.6**
Exacerbation
 Type 124 (60)101 (50)ns
 Type 25 (12)36 (18)ns
 Type 311 (28)63 (32)ns
Abrupt onset of exacerbation0 (0)58 (29) #
Confusion3 (8)12 (6)ns
Headache24 (60)100 (50)ns
Myalgia/arthralgia22 (55)74 (37)<0.03
Nausea/vomiting6 (15)24 (12)ns
Abdominal pain14 (35)50 (25)ns
Diarrhoea4 (10)12 (6)ns
Fever (at any stage of disease)27 (68)142 (71)ns
  • Data are presented as value±sd or value (%) unless otherwise stated

  • : in accordance with the classification of Anthonisen et al. 6

  • **: p<0.01

  • #: p<0.0001