Table 2—

Assessment of epithelial integinty pre and post virus or sham inoculation

Cells with loss of ciliaCells extruding from surfaceCells with cytoplasmic blebbingCells with mitochondrial damage
Corona
 Day 028.1 (15.4–40.8)25.8 (21.5–30.1)15.1 (10.7–19.5)11.9 (5.4–18.4)
 Day 397.9 (93.8–101.9)*63.4 (51.5–75.3)*36.3 (24.2–48.4)*44.2 (33.8–54.6)*
Sham
 Day 031.9 (26.4–37.4)25.7 (22.1–29.3)17.6 (10.2–25.0)10.4 (5.8–15.0)
 Day 323.3 (18.6–28)21.4 (20.9–21.9)17.1 (12.7–21.5)12.6 (3.7–21.5)
Group difference#
 Corona – sham79.2 (58.2–100.2)***41.9 (25.6–58.2)***21.7 (3.8–39.6)*30.1 (16.1–44.1)*
  • Data are presented as mean percentage (95% confidence interval)

  • #: difference between changes from baseline in the two groups, i.e. (day 3 − day 0)corona−(day 3 − day 0)sham

  • *: p<0.05

  • ***: p<0.001