Table 1—

Clinical features of chronic obstructive pulmonary disease (COPD) patients and controls

Patients with COPDControl subjectsp-;value
Subjects n8840
Sex M:F88:340:0
Age yrs66.9±1.672.9±1.0ns
Brinkman's index1201.6±70.11071.1±66.5ns
Pulmonary function
 FVC% pred77.4±2.295.9±3.8<0.0001
 FEV1 L1.1±0.12.4±1.4<0.0001
 FEV1/FVC%47.1±1.385.1±1.6<0.0001
  • Data are presented as the mean±sem

  • Brinkman's index: the number of cigarettes·day−1×the number of years

  • FVC: forced vital capacity; FEV1: forced expiratory volume in one second

  • NS: nonsignificant