Relevant parameters in three ventilated infants with respiratory syncytial virus bronchiolitis before and 24 h after first dose of recombinant human deoxyribonuclease RhDNase
| Patient 3 | Patient 4 | Patient 5 | |
| Sex | M | M | M |
| Gestational age weeks | 33 | 25 | 37 |
| Postconceptional age weeks | 37 | 54 | 39 |
| Radiograph before DNase | Atelectasis RUL, RML, LUL | Atelectasis RUL, LUL | Atelectasis RUL |
| Radiograph after DNase | General improvement of aeration | Resolution of atelectasis of RUL | Improved aeration of RUL |
| Maximum peak inspiratory pressure cmH2O before/after DNase | 23/21 | 30/25 | 25/24 |
| FI,O2 % before/after DNase | 60/35 | 80/70 | 40/37 |
| Cardiac beats frequency min−1 | |||
| before/after DNase | 168/151 | 150/135 | 155/139 |
| Pa,CO2 kPa | |||
| before/after DNase | 8.5/6.9 | 8.1/6.2 | 7.9/7.5 |
| Days on ventilator before DNase treatment | 1 | 1 | 5 |
| Complicating or predisposing | Prematurity, | Chronic Lung Disease, | Pneumonia |
| factors | Pneumonia | Prematurity, Pneumonia |
RUL: right upper lobe
LUL: left upper lobe
RML: right middle lobe
FI,O2: imspiratory oxysen fraction
Pa,CO2: carbon dioxide tension in arterial blood