Table 1

Demographics and baseline characteristics of the randomized patients

Patients n550371
Sex male/female366/184233/138
Age yrs65±965±9
Height cm171.1±9.6170.5±9.5
Weight kg76.9±17.775.5±17.5
Smoking history pack-yrs63±3159±30
Duration of disease yrs8.6±7.48.1±6.8
FEV1 L1.04±0.411.00±0.44
FEV1 % pred39.1±13.738.1±14.1
FVC L2.31±0.792.23±0.78
FEV1/FVC %45.8±11.645.5±11.6
Prestudy medication for COPD
Anticholinergics302 (55)217 (59)
β2-agonist, inhaled546 (99)368 (99)
Inhaled steroids239 (44)149 (40)
Oral steroids31 (6)33 (9)
Theophylline123 (22)94 (25)
  • Data are presented as mean±sd unless otherwise indicated

  • No significant differences were seen between the two groups

  • FEV1: forced expiratory volume in one second

  • FVC: forced vital capacity

  • COPD: chronic obstructive pulmonary disease

  • % pred: percentage of the predicted value