Ipratropium | Tiotropium | Difference | 95% CI | p-value | |
SGRQ | |||||
Symptoms | 50.47±1.49 | 47.32±1.07 | −3.15±1.73 | −6.55–0.26 | 0.070 |
Activities | 56.21±1.17 | 55.07±0.84 | −1.14±1.36 | −3.82–1.53 | 0.401 |
Impacts | 35.23±1.14 | 30.95±0.81 | −4.28±1.32 | −6.87–−1.68 | 0.001 |
Total | 44.20±0.97 | 40.90±0.69 | −3.30±1.13 | −5.51–−1.09 | 0.004 |
SF-36 | |||||
Physical function | 52.20±1.40 | 54.32±1.00 | 2.11±1.62 | −1.08–5.30 | 0.194 |
Role physical | 49.46±2.88 | 56.62±2.05 | 7.16±3.34 | 0.59–13.73 | 0.033 |
Bodily pain | 76.57±1.69 | 79.47±1.21 | 2.89±1.96 | −0.96–6.75 | 0.141 |
General physical health | 47.01±1.29 | 49.89±0.92 | 2.88±1.50 | −0.06–5.82 | 0.055 |
Physical health summary | 38.49±0.59 | 40.16±0.42 | 1.68±0.69 | 0.33–3.02 | 0.015 |
Vitality | 57.56±1.25 | 60.35±0.89 | 2.79±1.45 | −0.06–5.64 | 0.055 |
Social function | 74.68±1.75 | 76.07±1.25 | 1.39±2.02 | −2.59–5.37 | 0.493 |
Role emotional | 63.86±2.95 | 70.29±2.10 | 6.44±3.42 | −0.28–13.15 | 0.060 |
General mental health | 75.40±1.17 | 76.12±0.84 | 0.71±1.36 | −1.96–3.39 | 0.600 |
Mental health summary | 50.90±0.70 | 51.82±0.50 | 0.93±0.82 | −0.68–2.53 | 0.258 |
TDI | |||||
Focal score | −0.44±0.23 | 0.46±0.16 | 0.90±0.26 | 0.37–1.41 | 0.001 |
Data are presented as mean±sem or range
CI: confidence interval