Indications |
Severe respiratory failure in spite of optimal medical therapy |
Severely impaired quality of life |
Patient positively wants a transplant |
Strong contraindications |
Active aspergillus or mycobacterial infection |
Noncompliance with treatment |
Prednisolone therapy>10 mg·day−1 |
Other end-organ failure |
Gross malnutrition |
HIV |
Malignancy within 5 yrs |
Hepatitis B or C |
Burkholderia cepacia Genomovar type III |
Significant osteoporosis |
Significant osteoporosis |
Drug or alcohol addiction |
Risk factors |
Pre-operative ventilation (intubated) |
Previous thoracic surgery, especially pleurectomy |
Chemical pleurodesis, especially talc |
Severe liver disease |
HIV: human immunodeficiency virus