Table 2—

Between group comparisons and equivalence tests

% changeEstimate of effect size (treatment difference)p-value for equivalence (within 10%)Conclusion (α=0.025)
NMeansdmeanse95%cit-testMann-Whitney
BMI o.d. 242.853.09−0.0070.978−1.65<0.000001Eq.
t.i.d. 132.853.86
FVC % o.d. 3032.6439.3910.31−7.860.0330.013Eq.
t.i.d. 1623.229
FEV1 % o.d. 3029.536.93.949.48−11.9–∞0.3400.385ns
t.i.d. 1625.531.8
FEF25–75% o.d. 3026.244.31.1811.3−17.8–∞0.164ns
t.i.d. 162537.7
Score o.d. 21−47.429.74.019.95−∞–20.80.276ns
t.i.d. 9−51.428.6
WCC o.d. 25−1827.712.788.11−∞–26.40.6330.540ns
t.i.d. 14−30.826.2
Neut % o.d. 25−13.417.92.295.52−∞–11.60.0850.159ns
t.i.d. 14−15.713.4
CRP o.d. 23−45.338.8−19.511.0−∞–−1.090.0050.002Eq.
t.i.d. 15−25.834.1
Potassium o.d. 274.289.910.8732.82−4.80–6.550.0002 and 0.001Eq.
t.i.d. 153.49.93
Magnesium o.d. 23−113.42.294.32−6.54–11.110.004 and 0.0420.004 and 0.007Eq.
t.i.d. 12−3.296.69
Creatinine o.d. 275.4518.44.556.43−8.4–17.50.014 and 0.2000.004 and 0.200ns
t.i.d. 150.89827.6
  • CI: confidence interval

  • ∞: infinity

  • BMI: body mass index

  • o.d.: once-daily

  • t.i.d.: twice-daily

  • FVC: forced vital capacity

  • FEV1: forced expiratory volume in one second

  • FEF25–75%: forced mid-expiratory flow

  • Score: clinical score

  • WCC: white cell count

  • Neut: neutrophil count

  • CRP: C-reactive protein

  • Eq.: equivalent

  • ns: not significant