Table 2—

Sputum cell counts in acute asthma

Visit 1Visit 2
Nebulizer time min2.6±1.72.8±1.94.8±1.64.9±1.6
Neutrophils %31.6±2.563.1±3.236.6±239.8±1.6
Eosinophils %7.2±3.31.5±3.42.5±2***1.2±6.7
Macrophages %40.5±1.818.2±3.744.7±1.545.7±2
Lymphocytes %1.1±2.21.1±2.51.7±21±3
Epithelial cells %2.7±2.73.3±5.51.4±1.32.2±6.1
Squamous cells %4.9±2.74.6±3.15±3.34.4±1.2
IL-8 ng·mL−120.9±5.535±3.711.8±6.117.8±6.1
IL-5 positive cells %15.6±1.88.4±1.62±0.41.4±1.8
ECP ng·mL−13072±553090±49460±5***398±18
Neutrophil elastase µg·mL−1169±3.33129±7.4*100±2.5120±9.6***
LDH IU·mL−1182±2.2550±16*54±12.7***64±1.9***
  • Data are presented as mean±sd

  • TCC: total cell count

  • IL: interleukin

  • ECP: eosinophil cationic protein

  • LDH: lactate dehydrogenase

  • IU: international units. The analysis was carried out using unpaired t-tests on log-transformed data

  • *: p<0.05, significantly higher than subjects with noninfective acute asthma at Visit 1

  • #: p<0.05, significantly higher than subjects with infection and acute asthma at Visit 1

  • ***: p<0.001, significantly lower than Visit 1