Table 1

clinical characteristics and experimental details of subjects

SubjectSexAge yrsIS#µg·day−1FEV1 L (% pred)FEV1/FVC value (% pred)PD15 Unit +Exposure Order
1F422002.15 (71)0.72 (83)3.5Air:1000 µg·m−3:100 µg·m−3
2F294002.93 (86)0.71 (82)100100 µg·m−3:Air:1000 µg·m−3
3F24nil3.12 (92)0.84 (96)64100 µg·m−3:1000 µg·m−3:Air
4F21nil2.97 (103)0.90 (103)36Air:100 µg·m−3:1000 µg·m−3
5F305002.65 (87)0.81 (93)2201000 µg·m−3:Air:100 µg·m−3
6F21nil3.33 (98)0.86 (98)411000 µg·m−3:100 µg·m−3:Air
7M54nil2.77 (73)0.71 (89)5100 µg·m−3:Air:1000 µg·m−3
8M17nil3.94 (98)0.85 (91)15001000 µg·m−3:100 µg·m−3:Air
9M394004.04 (98)0.74 (90)481000 µg·m−3:Air:100 µg·m−3
10F294002.82 (86)0.77 (88)24Air:1000 µg·m−3:100 µg·m−3
11F32nil3.49 (112)0.86 (100)8100 µg·m−3:1000 µg·m−3:Air
12F40nil2.12 (92)0.73 (85)7Air:100 µg·m−3:1000 µg·m−3
13M27nil3.97 (94)0.82 (98)17100 µg·m−3:Air:1000 µg·m−3
  • IS: inhaled steroid

  • FEV1: forced expiratory volume in one second

  • FVC: forced vital capacity

  • % pred: percentage of predicted

  • PD15: provocative dose causing a 15% fall in FEV1

  • F: female

  • M: male

  • #: IS µg·day−1of beclomethasone or equivalent

  • : subjects who failed to complete the study

  • +: 1 breath unit defined as five inhalations of a 50 unit·mL−1 solution (arbitrary units)