Table 3—

Effects of different pressurization rates (PR) at 15 cmH2O of pressure support ventilation (PSV)

CharacteristicPR
LowestLowBaselineHighHighest
RR bpm31±9#23±727±727±731±9
VT ml278±89¶,##433±106##430±92##433±104##367±82##
V'e L·min−18.3±2.49.9±3.211.4±3.311.2±2.410.9±2.4
ti s1.1±0.3*1.1±0.40.9±0.20.8±0.20.8±0.2
ti/ttot0.53±0.080.45±0.080.38±0.040.35±0.030.38±0.06
tPSV s1.0±0.30.7±0.20.4±0.20.2±0.130.2±0.2+
PIF mL·s−1481±126¶,##673±191¶,##860±167##943±154##1121±175#,##
Dyspnoea cm3.7±1.8§ (2–7)1.5±1.5 (0–5)1.4±1.4 (0–5)2.6±1.5 (0–5)3.1±1.3f (1–5)
PTP cmH2O×s/min276±127¶,## (165–477)88±92## (21–268)67±67## (2–151)60±62## (4–191)101±100## (7–325)
WOB·min−1 J·min−110.6±7.4¶,## (2.9–23.4)4.9±6.5## (0.2–17.1)4.6±5.3## (0.2–14.9)4.0±5.1## (0.3–14.6)5.6±5.6## (0.2–12.8)
WOB·L−1 J·L−11.2±0.6¶,## (0.5–2.1)0.4±0.5## (0.04–1.3)0.3±0.3## (0.01–1)0.3±0.3## (0.04–1.2)0.5±0.5## (0.08–1.5)
PEEPi cmH2O1.6±1.11.5±0.91.0±1.20.9±0.61.7±1.6
P0.1 cmH2O3.5±21.7±1.41.5±1.21.9±1.42.0±1.3
  • Data are presented as mean±sd (range)

  • RR: respiratory rate

  • bpm: breaths·min−1

  • VT: tidal volume

  • V’e: minute ventilation

  • ti: inspiratory time

  • ti/ttot: duty cycle

  • tPSV: time to reach pressure support level

  • PIF: peak inspiratory flow

  • dyspnoea: Borg's dyspnoea scale

  • PTP: pressure time product

  • WOB·min−1: work of breathing per minute

  • WOB·L−1 work of breathing per L of ventilation

  • PEEPi: dynamic intrinsic positive end-expiratory pressure

  • P0.1: mouth occluded airway pressure at 0.1 s

  • All p-values are <0.05 for the following: #: versus low PR

  • : versus low, baseline, high, highest PR

  • *: versus high, highest PR

  • +: versus baseline

  • §: versus low, baseline, high PR

  • f: versus low, baseline PR

  • ##: versus PSV 5