Characteristic | PR | ||||
Lowest | Low | Baseline | High | Highest | |
RR bpm | 31±9# | 23±7 | 27±7 | 27±7 | 31±9 |
VT ml | 278±89¶,## | 433±106## | 430±92## | 433±104## | 367±82## |
V'e L·min−1 | 8.3±2.4¶ | 9.9±3.2 | 11.4±3.3 | 11.2±2.4 | 10.9±2.4 |
ti s | 1.1±0.3* | 1.1±0.4¶ | 0.9±0.2 | 0.8±0.2 | 0.8±0.2 |
ti/ttot | 0.53±0.08¶ | 0.45±0.08¶ | 0.38±0.04 | 0.35±0.03 | 0.38±0.06 |
tPSV s | 1.0±0.3¶ | 0.7±0.2¶ | 0.4±0.2 | 0.2±0.13 | 0.2±0.2+ |
PIF mL·s−1 | 481±126¶,## | 673±191¶,## | 860±167## | 943±154## | 1121±175#,## |
Dyspnoea cm | 3.7±1.8§ (2–7) | 1.5±1.5 (0–5) | 1.4±1.4 (0–5) | 2.6±1.5 (0–5) | 3.1±1.3f (1–5) |
PTP cmH2O×s/min | 276±127¶,## (165–477) | 88±92## (21–268) | 67±67## (2–151) | 60±62## (4–191) | 101±100## (7–325) |
WOB·min−1 J·min−1 | 10.6±7.4¶,## (2.9–23.4) | 4.9±6.5## (0.2–17.1) | 4.6±5.3## (0.2–14.9) | 4.0±5.1## (0.3–14.6) | 5.6±5.6## (0.2–12.8) |
WOB·L−1 J·L−1 | 1.2±0.6¶,## (0.5–2.1) | 0.4±0.5## (0.04–1.3) | 0.3±0.3## (0.01–1) | 0.3±0.3## (0.04–1.2) | 0.5±0.5## (0.08–1.5) |
PEEPi cmH2O | 1.6±1.1 | 1.5±0.9 | 1.0±1.2 | 0.9±0.6 | 1.7±1.6 |
P0.1 cmH2O | 3.5±2¶ | 1.7±1.4 | 1.5±1.2 | 1.9±1.4 | 2.0±1.3 |
Data are presented as mean±sd (range)
RR: respiratory rate
bpm: breaths·min−1
VT: tidal volume
V’e: minute ventilation
ti: inspiratory time
ti/ttot: duty cycle
tPSV: time to reach pressure support level
PIF: peak inspiratory flow
dyspnoea: Borg's dyspnoea scale
PTP: pressure time product
WOB·min−1: work of breathing per minute
WOB·L−1 work of breathing per L of ventilation
PEEPi: dynamic intrinsic positive end-expiratory pressure
P0.1: mouth occluded airway pressure at 0.1 s
All p-values are <0.05 for the following: #: versus low PR
¶: versus low, baseline, high, highest PR
*: versus high, highest PR
+: versus baseline
§: versus low, baseline, high PR
f: versus low, baseline PR
##: versus PSV 5