Table 2—

Nasal potential difference (PD) results of cystic fibrosis (CF) patients, control, patients with atypical CF disease, and patients with questionable CF disease

Patients nBasal PD mVΔAmiloride mVΔAmiloride %ΔIso+chloride-free mV
Non-CF50−16±510±461±18−12±7
CF31−49±13***35±11***72±13*3±6*
Atypical CF11−35±16***25±10***73±18*0±2*
QCF70−23±1013±854±19−6±5
QCF-CF24−30±1318±1260±20−1±3
QCF-non CF46−19±5**10±4**51±18−9±4**
  • Data are presented as mean±sd

  • Iso: isoprokerenol

  • CF: cystic fibrosis

  • QCF: questionable cystic fibrosis

  • QCF-CF: questionable CF with abnormal PD

  • QCF-non-CF: questionable CF with normal PD

  • *p<0.05, for the comparison with non-CF

  • **p<0.001, for the comparison between QCF-non-CF and QCF-CF

  • ***p<0.001, for the comparison with non-CF