Table 3—

Spearman correlation coefficients (rho) for relationships between disease-specific health status and measures of lung function and high-resolution computed tomography pixel index

St. George's Respiratory Questionnaire
SymptomsActivityImpactsTotal
Lung function
 FEV1−0.45−0.60−0.47−0.55
sGaw−0.46−0.66−0.52−0.60
 RV/TLC0.470.510.490.52
TL,CO−0.43−0.57−0.46−0.53
KCO−0.36−0.43−0.39−0.43
HRCT pixel index
 Upper zone inspiratory0.310.420.310.38
 Upper zone expiratory0.380.530.370.46
 Lower zone inspiratory0.310.440.360.39
 Lower zone expiratory0.410.580.440.50
  • FEV1: forced expiratory volume in one second

  • sGaw: specific airways conductance

  • RV: residual volume

  • TLC: total lung capacity

  • TL,CO: transfer factor of the lung for carbor monoxide

  • KCO: carbor monoxide transfer coefficient

  • expressed as a percentage of predicted

  • percentage of pixels <−910 HU

  • All correlations are highly significant (p<0.001)