Table 2—

Spearman correlation coefficients (rho) for the relationship between high-resolution computed tomography (HRCT) and lung function

HRCT pixel index
Upper zonelower zone
InspiratoryExpiratoryInspiratoryExpiratory
FEV1−0.60−0.72−0.64−0.75
FEV1/VC−0.72−0.79−0.70−0.78
FEF25%–75%−0.60−0.69−0.70−0.76
sGaw−0.67−0.76−0.68−0.76
TLC0.630.700.540.61
RV0.610.580.430.41
RV/TLC0.470.580.460.56
T L,CO −0.76−0.81−0.64−0.72
K CO −0.79−0.77−0.61−0.62
  • FEV1: forced expiratory volume in one second

  • VC: vital capacity

  • FEF25%–75%: forced midexpiratory flows

  • sGaw: Specific airways conductance

  • TLC: total lung capacity

  • RV: residual volume

  • TL,CO: transfer factor of the lung for carbor monoxide

  • KCO: carbor monoxide transfer coefficient

  • expressed as % predicted

  • percentage of pixels <−910 HU

  • All correlations are highly significant (p<0.001)