forced expiratory volume in one second FEV1 and Borg score at baseline and at reaching a methacholine induced ≥30% fall in FEV1
| Subjects n | Baseline FEV1 | FEV1 after methacholine | Baseline Borg score | Borg score after methacholine | PD30+ | Dyspnoea perception |
| Formoterol | 17 2.99±0.74 | 1.73±0.52 | 0.4±0.7 | 2.65±1.44 | 12.4 mg | 0.067±0.040 |
| (−42.2±8.3%) | 0.0 (0–2) | 3.0 (0.5–5) | ||||
| Salmeterol | 16 2.98±0.73 | 1.83±0.56 | 0.4 ±0.6 | 2.78±1.37 | 7.9 mg | 0.076±0.040 |
| (−38.4±9.5%) | 0.0 (0–2) | 3.0 (0.5–4) | ||||
| Placebo | 16 2.67±0.65 | 1.68±0.46 | 0.6±0.6 | 2.66±1.25 | 3.7 mg | 0.074±0.036 |
| (−37.0±5.8%) | 0.5 (0–2) | 3.0 (0.5–5) |
Data are presented as mean±sd
Borg score also as median (range)
Dyspnoea perception is presented as %−1. Baseline represents the value one hour after inhaling the last dose of study medication
PD30+: cumulative dose of methacholine administered at ≥30% fall in FEV1 (geometric mean)