6-month analysis | 12-month analysis | |||
None/mild | Moderate/severe | None/mild | Moderate/severe | |
Patients n | 127 | 42 | 86 | 32 |
Age at diagnosis yrs | 63.8±9.9 | 64.0±9.6 | 62.8±10.1 | 62.6±9.8 |
Male | 94 (74.0) | 33 (78.6) | 65 (75.6) | 23 (71.9) |
Ever tobacco use | 89 (70.1) | 42 (100) | 57 (66.3) | 32 (100) |
Tobacco pack-yrs | 21.0±25.0 | 46.4±28.4 | 20.8±25.8 | 45.4±26.5 |
Surgical lung biopsy | 98 (77.2) | 20 (47.6) | 71 (82.6) | 17 (53.1) |
Follow-up yrs | 5.1 (4.7–6.1) | 5.3 (3.3–7.9) | 5.3 (5.0–7.0) | 6.0 (2.5–6.8) |
HRCT type | ||||
Volumetric | 35 (27.6) | 16 (38.1) | 17 (19.8) | 9 (28.1) |
Incremental | 91 (71.1) | 26 (61.9) | 69 (80.2) | 23 (71.9) |
Emphysema | ||||
None | 83 (65.4) | 63 (73.3) | ||
Mild | 44 (34.6) | 23 (26.7) | ||
Moderate | 32 (76.2) | 27 (84.4) | ||
Severe | 10 (23.8) | 5 (15.6) | ||
Pulmonary function | ||||
FEV1 % pred | 77.4±16.9 | 84.0±16.2 | 78.1±17.4 | 88.5±19.6 |
FVC % pred | 64.8±14.3 | 76.2±15.2 | 65.3±14.8 | 79.2±16.1 |
FEV1/FVC ratio | 0.84±0.06 | 0.78±0.07 | 0.85±0.05 | 0.79±0.07 |
DL,CO % pred | 45.8±14.3 | 42.2±16.0 | 46.7±15.8 | 46.3±15.3 |
CPI | 53.2±10.8 | 51.7±12.5 | 52.6±11.7 | 49.1±11.5 |
Data are presented as mean±sd, n (%) or median (95% CI), unless otherwise stated. HRCT: high-resolution computed tomography; FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; DL,CO: diffusing capacity of the lung for carbon monoxide; CPI: composite physiologic index.