Cystic fibrosis infant bronchoalveolar lavage profiles from the right middle and lingula lobes
| ≥1×105 cfu·mL−1 | <1×105 cfu·mL−1 in both lobes | ||||
| RML | p-value | Lingula | RML | Lingula | |
| Subjects n | 6 | 24 | |||
| Recovery % | 34 | 0.88 | 32 | 41 | 44 |
| CI | 19–58 | — | 23–45 | 34–50 | 36–51 |
| p-value | 0.42 | — | 0.09 | ||
| Pathogen cfu·mL−1 | 4.6×105 | 0.003 | 3.2×102 | 2.6×101 | 2.1×101 |
| CI | 2.5–86 | — | 0.04–22.3 | 0.4–11.6 | 0.3–7.8 |
| p-value | <0.001 | — | 0.15 | — | — |
| Total cell count ×104·mL−1 | 171 | 0.09 | 106 | 136 | 120 |
| CI | 124–260 | — | 42–265 | 100–184 | 83–172 |
| p-value | 0.19 | — | 0.77 | — | — |
| Macrophages % | 30 | 0.29 | 44 | 68 | 66 |
| CI | 27–43 | — | 12–75 | 59–76 | 59–74 |
| p-value | <0.001 | — | 0.14 | — | — |
| Neutrophils % | 67 | 0.29 | 52 | 28 | 29 |
| CI | 55–79 | — | 21–84 | 21–35 | 22–36 |
| p-value | <0.001 | — | 0.12 | — | — |
| Lymphocytes % | 4.0 | 0.85 | 3.8 | 3.0 | 3.2 |
| CI | 0.4–7.6 | — | 0.4–7.2 | 1.9–4.0 | 2.3–4.0 |
| p-value | 0.51 | — | 0.65 | — | — |
| IL-8 pg·mL−1 | 1104 | 0.67 | 906 | 229 | 175 |
| CI | 233–5236 | 302–2716 | 114–459 | 108–283 | |
| p-value | 0.05 | 0.01 | — | — | |
≥1×105 cfu·mL−1 in the right middle lobe only
paired t-test between right middle and lingula lobes in the 6 subjects with ≥1×105 cfu·mL−1 in the right middle lobe only
2-sample t-test between right middle lobes and between lingula lobes in the 6 subjects with unilateral (right middle lobe only) bacterial counts ≥1×105 cfu·mL−1 and the 24 subjects with 1×105 cfu·mL−1 in both lobes. IL-8: interleukin-8