Table 3—

Comparison of clinical and cytokine data between patients with pneumonia and recovery of a potentially pathogenic micro-organism (PPM) in bronchoalveolar lavage (BAL), and patients with pneumonia and sterile BAL cultures

Before BAL12 h24 h
PPM recovered (n=11)
 Mean arterial blood pressure, mmHg88 (67–110)77 (65–108)82 (73–100)
 Axilliary body temperature, °C36.2 (35.6–37.6)37.0 (35.8–38.6)36.8 (36.2–38.0)
 Cardiac frequency beats·min−195 (80–145)100 (75–125)105 (70–135)
 TNF-α, pg·mL−139 (13–88)41 (0–64)37.5 (15–63)
 IL-1β, pg·mL−12 (0–12)3 (0–14)4 (0–122)
 IL-6, pg·mL−1297 (47–4300)359 (53–3778)194 (23–924)
BAL sterile or no PPM (n=7)
 Mean arterial blood pressure, mmHg68 (57–107)70 (57–110)73 (62–112)
 Axilliary body temperature, °C37.2 (35.8–38.0)36.4 (35.8–38.0)36.8 (35.0–38.8)
 Cardiac frequency beats·min−185 (60–115)90 (50–105)85 (80–110)
 TNF-α, pg·mL−122 (10–47)25 (14–44)23.5 (0–48)
 IL-1β, pg·mL−10 (0–13)2 (0–31)4 (0–43)
 IL-6, pg·mL−178 (9–1424)53 (16–1487)43 (11–596)
  • Data are presented as median (range)

  • TNF-α: tumour necrosis factor α

  • IL: interleukin

  • PPM: potentially pathogenic micro-organism

  • microbiological results were not available in 2/20 (10%) patients with pneumonia. No significant differences were observed for the comparison between time points or between patients with and without recovery of a PPM.