Table 2—

Mean systemic cytokine levels before bronchoalveolar lavage (BAL), and 12 h and 24 h thereafter for all the patients and separately for patients with pneumonia and controls

Concentration pg·mL−1Before BAL12 h24 h
All patients (n=30)
 TNF-α22 (0–88)19 (0–64)25 (0–63)
 IL-1β0 (0–32)0 (0–31)2 (0–122)*
 IL-6108 (0–4300)84 (12–3778)112 (5–1976)
With pneumonia (n=20)
 TNF-α35 (10–88)35 (0–64)31 (0–36)
 IL-1β0 (0–13)3 (0–31)5 (0–122)#
 IL-6226 (9–4300)156 (16–3778)194 (11–1976)
Controls (n=10)
 TNF-α17 (0–33)15.5 (0–21)¶19 (0–43)
 IL-1β1 (0–32)0 (0–13)+_auth;0 (0–7)
 IL-653 (0–346)55 (12–159)46 (5–296)
p-values for comparison between patients with and controls
 TNF-α0.0100.0020.037
 IL-1β>0.2>0.2>0.2
 IL-60.0170.0210.074
  • Values were compared at different time points and between patients with and without pneumonia (exact p-values are given if p<0.2)

  • Data are presented as median (range)

  • TNF-α: tumour necrosis factor α

  • IL: interleukin

  • p=0.150 versus baseline

  • p=0.054 versus baseline

  • p=0.123 versus baseline

  • p=0.068 versus baseline

  • p-value calculated with Mann-Whitney U-Test.