Table 1—

Clinical data of patients investigated

With pneumonia (n=20)Without pneumonia (n=10)p-value
Age yrs66.5 (53–76)67.5 (54–76)0.643
Gender male, n (%)17 (85)8 (80)1.0
SAPS II33 (12–52)30 (18–56)0.983
Pa,O2/FI,O2192 (65–256)293 (205–473)0.001
Duration of mechanical ventilation prior to the study, h52 (18–408)60 (24–298)0.619
Leukocyte count, ×109·L−114.5 (1.9–26.5)10.5 (7.0–16.8)0.198
Corticosteroids, n (%)11 (55)5 (50)1.0
Prior antibiotics, n (%)20 (100)8 (80)0.103
Mortality, n (%)10 (50)3 (30)0.297
  • All patients received mechanical ventilation during the study and pneumonia was defined according to clinical criteria

  • Data are presented as median (range) unless otherwise stated

  • Mann-Whitney U-test and Chi-squared or Fisher's exact test for quantitative and categorical variables, respectively

  • SAPS II: simplified acute physiology score II

  • Pa,O2/FI,O2: arterial oxygen partial pressure to inspired oxygen fraction ratio.