Ventilatory parameters and blood gases (mean±sd) in intact (I) awake spontaneously breathing and in paralysed (P) mechanically-ventilated animals
| Inspired mixtures | ||||
| Ventilatory parameter | Control room air | Hypoxia 12% O2 | Hypercapnia 5% CO2 | Hypoxia+hypercapnia 5% CO2 |
| VT mL | ||||
| I | 0.526±0.81 | 0.797±0.23 | 0.941±0.21 | 1.160±0.18 |
| P | 0.510±0.11 | 0.800±0.26 | 0.910±0.26 | 1.100±0.2 |
| f beats·min-1 | ||||
| I | 82±12 | 99±15 | 128±12 | 146±23 |
| P | 85±5 | 98±14 | 125±6 | 134±6 |
| V'E mL·min·kg-1 | ||||
| I | 163±30 | 278±87 | 480±19 | 610±141 |
| P | 164±41 | 280±35 | 387±77 | 503±54 |
| pH | ||||
| I | 7.46±0.04 | 7.53±0.02 | 7.36±0.02 | 7.38±0.03 |
| P | 7.44±0.02 | 7.47±0.08 | 7.33±0.02 | 7.28±0.05 |
| Pa,O2 mmHg | ||||
| I | 95.0±8.4 | 44.8±1.8 | 118.0±2.8 | 68.0±4.2 |
| P | 82.0±2.3 | 42.7±5.5 | 117.0±8.6 | 55.0±5.3 |
| Pa,CO2 mmHg | ||||
| I | 34±3.8 | 29±0.8 | 44±2.1 | 42±1.2 |
| P | 32±4.2 | 25±3.3 | 45±1.5 | 43±1.9 |
No significant difference between I and P was observed in any of the above parameters.