Table 2

Prospective series on the use of 18f-fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET) in the differential diagnosis of lung nodules or masses

First author [Ref.]YearnMethod of analysisSensitivity %Specificity %Accuracy %Prevalence %
Sazon 301996107Visual100528977
Lowe 31199889Visual98698967
Semiquantitative929091
Duhaylongsod 32199587Semiquantitative97829268
Gupta 33199661Semiquantitative93889274
Nackaerts 34199752Semiquantitative94829067
Patz 35199351Semiquantitative891009265
Bury 36199650Visual100889666
Slosman 37199336Visual94608986
Dewan 38199330Visual95809067
Kubota 39199022Semiquantitative83908655
Gupta 40199220Semiquantitative10010010065
Gupta 41199819Visual10010010063
Semiquantitative8310089
  • Visual: visual interpretation on whole-body images; Semiquantitative: using a threshold of a semiquantitative measure of FDG-uptake (e.g. standardized uptake value); prevalence: proportion of malignant cases in the total group of studied nodules.