Table 3

Results of Cox regression analysis relating survival time to individual selected variables

VariableHazard ratio (95% CI)p-value
NYHA class0.60 (0.11–3.20)0.55
VC L0.97 (0.93–1.00)0.22
FVC L0.99 (0.95–1.03)0.51
FEV1 L0.98 (0.94–1.03)0.47
DL,CO mL·min−1·mmHg−10.99 (0.93–1.05)0.74
Arterial PO20.97 (0.91–1.03)0.28
Arterial PCO20.86 (0.74–1.01)0.07
Arterial pH1.28 (0.93–1.76) (per 0.01 increase in pH value)0.13
Sa,O2-rest %0.91 (0.81–1.01)0.09
Sa,O2-exercise %0.92 (0.85–0.99)0.03
ΔSa,O2%1.26 (1.04–1.53) (per each 1% decrease)0.02
Distance m0.82 (0.63–1.05) (per 50 meters increase in distance)0.11
mRAP mmHg1.09 (0.95–1.24)0.19
mPAP mmHg1.23 (1.03–1.47)0.33
CO L·min−10.66 (0.38–1.14)0.14
PVR Wood units1.12 (1.01–1.26)0.04
  • NYHA: New York Heart Association; VC: slow vital capacity; FVC: forced vital capacity; FEV1: forced expired volume in the first second; DL,CO: diffusing capacity for carbon monoxide; PO2: arterial oxygen tension; PCO2: arterial carbon dioxide tension; Sa,O2-rest: oxygen saturation rest; Sa,O2-exercise: trough of oxygen saturation during six-minute walk test; ΔSa,O2: difference between resting and trough oxygen saturation; mRAP: mean right atrial pressure; mPAP: man pulmonary artery pressure; CO: cardiac output; PVR: pulmonary vascular resistance.