Table 2—

Interleukin‐4 (IL‐4) antagonism; possible targets

IL‐4 neutralization
 anti‐IL‐4 antibodies
 soluble IL‐4 receptor
IL‐4 receptor α chain activation
 anti‐IL‐4Rα antibodies
 IL‐4 mutant proteins (IL‐4.Y124D, Bay 16-9996)
IL‐4 receptor α chain signal transduction
 inhibition of? (STAT6) (antisense oligonucleotides, supressor of cytokine signalling‐1 (SOCS‐1))