Table 1

Demographic data of 42 human immunodeficiency virus-infected patients with nosocomial bacterial pneumonia (NBP) (cases) and 84 matched human immunodeficiency virus (HIV)-infected patients without nosocomial infections (controls)

CasesControls
Sex M:F31:1162:22
Mean age, yrs34.1±6.233.3±4.4
HIV risk behaviour %
Intravenous drug abuse26 (62)56 (67)
Homosexual contacts8 (19)14 (17)
Heterosexual contacts7 (17)12 (14)
Other1 (2)2 (2)
Stage of HIV infectiona %
A2 (5)5 (6)
B5 (12)10 (12)
C35 (83)69 *82)
Main reason for admission %
Gastrointestinal manifestations14 (33)28 (33)
Neurological syndromes12 (29)24 (29)
Fever of unknown origin10 (24)20 (24)
Neoplastic diseases6 (14)12 (14)
Mean hospital stay days30.1±10.115±4.9
Mean days to NBP14.3±19.6
Mean PMN cells·mm31278±10503278±1670
Mean T CD4+ cells·mm387.3±49.594.1±56.2
Mean HIV-RNAb cp·mL×10335.8 (0.5–650.5)29.5 (0.5–475.5)
PCP prophylaxis with CTX %35 (83)62 (74)
Antiretroviral therapy %
Monotherapy13 (31)18 (21)
2 RTI19 (45)34 (41)
HAART6 (14)23 (27)
No therapy4 (10)9 (11)
  • Data are presented as mean±sd or n (%), or mean (range). a: According to Centres for Diseases Control definition of acquired immunodeficiency syndrome; b: available after September 1996. cp: copies; CTX: cotrimoxazole; RTI: reverse transcriptase inhibitor; HAART: highly active antiretroviral therapy; PMN: polymorphonuclear; RNA: ribonucleic acid; PCP: Pneumocystis carinii; CTX: cotrimoxazole.