Healthy subjects | CF patients | |
Donors | 7 | 25 |
Age, years | 44±11.1 | 30.8±8.7 |
Female | 3 (43) | 7 (28) |
FEV1, L | 3.44±0.73 | 2.2±1.13 |
FEV1 % predicted | 95.8±6.0 | 54.9±21.8 |
CFTR genotype | ||
F508del/F508del | 13 (52) | |
F508del/other | 8 (32) | |
Other/other | 4(16) | |
Pseudomonas infection | ||
Negative | 2 (8) | |
Intermittent | 6 (24) | |
Chronic | 17 (68) | |
Pancreatic insufficiency | 23 (92) |
Data are presented as n, mean±sd or n (%). FEV1: forced expiratory volume in 1 s; CFTR: cystic fibrosis transmembrane conductance regulator.