TABLE 1

Demographic and clinical characteristics of healthy controls and patients with cystic fibrosis (CF) who donated sputum for rheology studies

Healthy subjectsCF patients
Donors725
Age, years44±11.130.8±8.7
Female3 (43)7 (28)
FEV1, L3.44±0.732.2±1.13
FEV1 % predicted95.8±6.054.9±21.8
CFTR genotype
 F508del/F508del13 (52)
 F508del/other8 (32)
 Other/other4(16)
Pseudomonas infection
 Negative2 (8)
 Intermittent6 (24)
 Chronic17 (68)
Pancreatic insufficiency23 (92)

Data are presented as n, mean±sd or n (%). FEV1: forced expiratory volume in 1 s; CFTR: cystic fibrosis transmembrane conductance regulator.