Clinical characteristics of the participants with and without widespread bronchiectasis
| Participants with widespread radiological bronchiectasis | Participants without widespread radiological bronchiectasis | p-value# | |
| Participants | 20 | 153 | |
| Number of lobes with radiological bronchiectasis median (interquartile range) | 3 (1) | 0 (2) | <2×10−16 |
| Meet clinical criteria for bronchiectasis¶ | 6 (30) | 20 (13) | 0.08 |
| Age years | 66±5 | 67±8 | 0.62 |
| Sex | 1 | ||
| Male | 17 (85) | 124 (81) | |
| Female | 3 (15) | 29 (19) | |
| Race | 0.63 | ||
| White | 15 (75) | 114 (74.5) | |
| Black | 3 (15) | 18 (11.8) | |
| Asian | 1 (5) | 4 (2.6) | |
| Other/unknown | 1 (5) | 17 (11.1) | |
| Smoking status | 1 | ||
| Current | 9 (45) | 66 (43.1) | |
| Former | 10 (50) | 80 (52.3) | |
| Unknown | 1 (5) | 7 (4.6) | |
| Smoking pack-years+ | 45±19 | 51±26 | 0.37 |
| FEV1 % predicted | 69±22 | 75±20 | 0.23 |
| FEV1/FVC | 0.6±0.2 | 0.6±0.1 | 1 |
| COPD | 14 (70) | 105 (69) | 1 |
| Malignancy | 0.31 | ||
| Yes | 4 (20) | 71 (46) | |
| No | 6 (30) | 45 (31) | |
| Unknown | 10 (50) | 37 (24) | |
| Radiological bronchiectasis | <0.001 | ||
| Yes | 20 (100) | 76 (50) | |
| No | 0 (0) | 77 (50) | |
| Traction bronchiectasis | 0.081 | ||
| Yes | 7 (35) | 23 (15) | |
| No | 12 (60) | 116 (76) | |
| Indeterminate | 1 (5) | 14 (9) | |
| Emphysema§ % | 16.2±14.7 | 13.8±16.7 | 0.71 |
| CT bronchiectasis score | 7.7±5.5 | 1.3±2.0 | <0.001 |
| Cough | 1 | ||
| Yes | 9 (45) | 68 (44) | |
| No | 9 (45) | 72 (47) | |
| Unknown | 2 (10) | 13 (9) | |
| Phlegm | 0.46 | ||
| Yes | 11 (55) | 65 (43) | |
| No | 8 (40) | 74 (48) | |
| Unknown | 1 (5) | 14 (9) | |
| Both cough and phlegm | 0.804 | ||
| Yes | 8 (40) | 47 (31) | |
| No | 12 (60) | 90 (59) | |
| Unknown | 0 (0) | 16 (11) | |
| Shortness of breath | 0.01 | ||
| Yes | 17 (85) | 81 (53) | |
| No | 2 (10) | 59 (39) | |
| Unknown | 1 (5) | 13 (9) |
Data are presented as n, mean±sd or n (%), unless otherwise stated. FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; CT: computed tomography. #: p-values calculated using ANOVA F-test or Fisher's exact test; ¶: missing values for 12 participants without widespread radiological bronchiectasis and two participants with widespread radiological bronchiectasis; +: missing values for two participants without widespread radiological bronchiectasis; §: missing values for 13 participants with widespread radiological bronchiectasis and 58 participants without widespread radiological bronchiectasis.